©2019 by ExoProTher Medical.

Time lapse imaging

R&D status

Consistent cancer cell apoptosis following one dose of EXO_002 in vitro

MTT viability assay (example)

Cells viability 72h after treatment with EXO_002. Strong response was observed. **ttest p<0.0005

Cell count and apoptotic staining

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Pre-clinical study – murine model

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Significantly prolonged survival

Mice colon cancer MC38 (p53 mut)

Black C57BL/6 male mice, 3mo old

Process development

  • Vesicles size distribution in EXO_002

  • Demonstrated preserved potency after one year storage at -40°C

  • Further experiments planned with more concentrated active substance; potency increased by factor of 10

Brownian motion