Scientific background
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Yevgeny Tendler, Alexander Tendler, Alexander Panshin. Magische kugel against cancer. Journal of Molecular Oncology Research (2021) Volume 5, Issue 2
https://www.alliedacademies.org/abstract/magische-kugel-against-cancer-15745.html
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Tendler, Y., Panshin, A. Features of p53 protein distribution in the corneal epithelium and corneal tear film. Sci. Rep. 10, 100051 (2020) https://doi.org/10.1038/s41598-020-67206-z
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Tang Q, Su Z, Gu W, Rustgi AK. Mutant p53 on the Path to Metastasis. Trends Cancer. 6(1), 62-73. (2020) doi: 10.1016/j.trecan.2019.11.004. Epub 2019 Dec 16. PMID: 31952783; PMCID: PMC7485681.
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Li M, Li S, Du C, Zhang Y, Li Y, Chu L, Han X, Galons H, Zhang Y, Sun H, Yu P. Exosomes from different cells: Characteristics, modifications, and therapeutic applications. Eur J Med Chem. 11, 207-112784 (2020)
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Walker, S. et al. Extracellular vesicle-based drug delivery systems for cancer treatment. Theranostics vol. 9(26), 8001-8017 (2019) doi:10.7150/thno.37097
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Perets, N., Hertz, S., London, M., Offen, D. Intranasal administration of exosomes derived from mesenchymal stem cells ameliorates autistic-like behaviors of BTBR mice. Mol Autism. 9, 57 (2018) doi: 10.1186/s13229-018-0240-6.
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Burdakov, V.S., Kovalev, R.A., Pantina, R.A. et al. Exosomes Transfer p53 between Cells and Can Suppress Growth and Proliferation of p53-Negative Cells. Cell Tiss. Biol. 12, 20–26 (2018). https://doi.org/10.1134/S1990519X18010030
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Parrales, A., Iwakuma, T. Targeting oncogenic mutant p53 for cancer therapy. Frontiers in Oncology. 5, 288–288 (2015)
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Rivli, N., Brosh, R., Oren, M., Rotter, V. Mutations in the p53 Tumor Suppressor Gene: Important Milestones at the Various Steps of Tumorigenesis. Genes Cancer. 2(4), 466-74. (2011) doi: 10.1177/1947601911408889.
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Almazov, V.P., Kochetkov, D.V., Chumakov, P.M. The use of p53 as a tool for human cancer therapy Mol Biol (Mosk). 41, 947–963 (2007)
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Tendler, Y., Panshin, A., Weisinger, G. & Zinder, O. Identification of cytoplasmic p53 protein in corneal epithelium of vertebrates. Exp. Eye Res. 82, 674–681 (2006).
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Pokroy, R., Tendler, Y., Pollack, A., Zinder, O. & Weisinger, G. P53 expression in the normal murine eye. Invest Ophthalmol. Vis. Sci. 43, 1736–41 (2002).
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Vogelstein, B. & Kinzler, K. W. P53 function and dysfunction. Cell. 70, 523–526 (1997).
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Lane, D. P. p53: guardian of the genome. Nature. 358, 15–16 (1992).